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663 HAZWOPER for General Site Workers IV
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Chemical Effects

The effects chemicals have on the various organs of the human body depend on several important factors:

  1. The form of the chemical substance, or mixture of substances: is the chemical a solid, liquid, or gas?
  2. How the chemical contacts the body: is the chemical ingested, inhaled, absorbed, or injected? Most common form of contact is inhalation.
Opened bottle of clearly marked hazardous poison laying on ground
A small dose from this bottle illustrates that "the dose makes the poison."
  1. The amount, or dose, the body receives: The amount of a substance received at one time. Dose is usually expressed as administered or absorbed dose (e.g., milligrams material/kilogram of body weight.
  2. How toxic the chemical is: Toxicity is the sum of adverse effects (acute or chronic injury to the human body) resulting from exposure to a material.

Knowledge Check Choose the best answer for the question.

2-5. Which term describes the amount of chemical that makes its way into the body?