IgE/histamine-mediated Allergy
The third and potentially most serious type of reaction associated with glove use is Type I or IgE/histamine-mediated allergy to allergenic glove protein. This type of reaction can involve mild, more-sever, or life-threatening symptoms.
Mild Symptoms: Localized reactions occur at the site of exposure.
- itching
- skin redness
- hives or rash
More-Severe Symptoms: Systemic symptoms that may indicate a serious latex allergy include the following:
- sneezing or coughing
- runny nose
- itchy, watery eyes
- scratchy throat
- difficulty breathing or wheezing
Life-Threatening Symptoms: The most serious allergic reaction to latex is anaphylaxis. An anaphylaxis reaction develops immediately after latex exposure in highly sensitive people. It rarely happens the first time someone is exposed. Signs and symptoms of anaphylaxis include:
- difficulty breathing or wheezing
- hives or swelling
- nausea and vomiting
- drop in blood pressure or rapid/weak pulse
- confusion, dizziness, or loss of consciousness
If any of these symptoms develop following an exposure to latex, medical treatment must be initiated immediately.
Knowledge Check Choose the best answer for the question.
1-4. Which symptom indicates a more-severe systematic latex allergy?
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