Skip to main content

Decontamination

Decontamination of a BSC must consist of surface cleaning with water and detergent, followed by a thorough rinsing. Spray cleaners should be avoided because of the risk of spraying the HEPA filter. Ordinary decontamination procedures which include fumigation with a germicidal agent, are inappropriate in a BSC because such procedures don't remove or deactivate the hazardous drugs. Below are some decontamination best practices:

  • Removable work trays should be lifted in the back of the BSC to be cleaned.
  • During cleaning, the worker should wear appropriate personal protective equipment (PPE) similar to those used for spills.
  • The exhaust fan/blower should be left on and cleaning should proceed from least to most contaminated areas.
  • The drain spillage trough area should be cleaned at least twice since it can be heavily contaminated.

Knowledge Check Choose the best answer for the question.

2-4. Which of the following is an appropriate decontamination practice for a biological safety cabinet (BSC)?